Comparative in vitro activity of oritavancin against Staphylococcus aureus strains that are resistant, intermediate or heteroresistant to vancomycin.

1. Galimand M, Courvalin P, Lambert T. Plasmid-mediated highlevel resistance to aminoglycosides in Enterobacteriaceae due to 16S rRNA methylation. Antimicrob Agents Chemother 2003; 47: 2565–71. 2. Doi Y, Arakawa Y. 16S ribosomal RNA methylation: emerging resistance mechanism against aminoglycosides. Clin Infect Dis 2007; 45: 88–94. 3. Bogaerts P, Galimand M, Bauraing C et al. Emergence of ArmA and RmtB aminoglycoside resistance 16S rRNA methylases in Belgium. J Antimicrob Chemother 2007; 59: 459–64. 4. Naas T, Lezzar A, Bentchouala C et al. Multidrug-resistant Salmonella enterica serotype Senftenberg isolates producing CTX-M b-lactamases from Constantine, Algeria. J Antimicrob Chemother 2005; 56: 439–40. 5. Gołebiewski M, Kern-Zdanowicz I, Zienkiewicz M et al. Complete nucleotide sequence of the pCTX-M3 plasmid and its involvement in spread of the extended-spectrum b-lactamase gene blaCTX-M-3. Antimicrob Agents Chemother 2007; 51: 3789–95. 6. Galimand M, Sabtcheva S, Courvalin P et al. Worldwide disseminated armA aminoglycoside resistance methylase gene is borne by composite transposon Tn1548. Antimicrob Agents Chemother 2005; 49: 2949–53. 7. Wu Q, Zhang Y, Han L et al. Plasmid-mediated 16S rRNA methylases in aminoglycoside-resistant Enterobacteriaceae isolates in Shanghai, China. Antimicrob Agents Chemother 2009; 53: 271–2.